Impact of the Switch from Ten to Five Dose Measles Rubella (MR) Vaccines in Kenya

On-going

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The study is currently implementing a parallel–cluster randomized trial across Vihiga, Homa Bay, and Kiambu counties—randomizing sub-counties into intervention and control arms across 470 health facilities—to evaluate whether switching from 10-dose to 5-dose MR vials (with 35,000 five-dose vials supplied by the National Vaccines and Immunization Program and accompanying healthcare-worker training) can improve vaccine coverage and reduce wastage, assess acceptability by healthcare workers, examine supply-chain operational factors, and lower the total cost per vaccinated child. It is collecting administrative and wastage data; conducting key-informant interviews, focus groups, and cold-chain assessments; and intends to analyze these using segmented time-series and regression models. It aims to provide local evidence to the Ministry of Health on the viability of switching from 10-dose to 5-dose measles-rubella vials.

Research Team: NIERA member Apollo Maima (PhD) and collaborators Professor Faith Okalebo (University of Nairobi), Doreen Othero (Innovia Research Consulting), Cameline Orlendo (KEMRI), and Edna Osano (Maseno University).

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